There have been multiple studies on blood types and COVID-19 risk. While the distribution of blood types is different in New York City than in Wuhan and Shenzhen, after controlling for other risk factors, they found that individuals with Type A blood were 34 percent more likely to test positive for the coronavirus, while having Type O or AB blood was associated with a lower probability of testing positive. - Case Studies Using this data, 23andMe launched their COVID-19 Severity Calculator last year. The most commonly reported reaction was a raised, sometimes itchy red rash, often at the site of the injection, which can occur up to a week or so after being vaccinated. What Are the Differences Between the Pfizer and Moderna COVID-19 Vaccines? A Vancouver study revealed people with blood types A, B or AB had worse outcomes than others. Experts have stressed the rarity of such cases estimating they may occur in about one in 100,000 young adults who get the jab a risk lower than the chance of dying in a road accident in a year. People react differently after being vaccinated. Indeed, coagulopathy (problems with bleeding disorders) is common in COVID-19, with dangerous blood clots being a hallmark of the disease. Information on this website is provided for informational purposes only and is a result of years of practice and experience by the author. Notably, she took danicopan throughout her first vaccination and did not experience breakthrough hemolysis. These cases have been mild and self-resolving. The severity of the COVID-19 disease Recent data suggests that people with blood type A have a significantly higher risk of acquiring COVID-19 than non-A blood types. Fatigue. You could . Or, they suggest, perhaps the genes associated with blood type also have some effect on the ACE2 receptor, the protein that allows the SARS-CoV-2 virus to infect human cells. This content is for informational and educational purposes only. MF 8 a.m. 8 p.m. Earlier this month the MHRA said that while not yet proved, there was growing evidence to suggest this syndrome could be caused by the AstraZeneca jab, while the European Medicines Agency said there was a possible link and noted the syndrome should be listed as a very rare side-effect of the vaccine. Why? But if you do choose to receive a bivalent booster within three months of your last sickness, you shouldn't expect to experience wildly different or worse side effects as compared to if you had waited, Dr. Martinello stresses. Use our Culture Starter to keep home fermenting simple and safe. Omicron vs. Delta: How the 2 COVID-19 Variants Compare, ShinglesHerpes ZosterInfection May Be Linked to the COVID-19 Vaccine. The latest data on blood type is still preliminary. Ann Intern Med. What are the most common COVID vaccine side effects? Registration is free. One of these areas contains genes that determine blood type along with other genes that are known to be associated with immune function. "Half of it is the same as the original vaccine," explains Richard Martinello, M.D., the medical director of infection prevention at Yale New Haven Health System. A comprehensive review of studies published in Seminars in Vascular Surgery in September 2021 examined peer-reviewed journal articles published from March 2020 to January 2021. 8 Potential Bivalent Vaccine Side Effects. Pain can be managed with acetaminophen, like Tylenol, or ibuprofen, Litwack said. Read said that for some people the process was without symptoms, but for others it generated these common side-effects. Women and younger adults tend to have more side effects than men or older adults do. Not necessarily. They include: tenderness, swelling, and. The risk for individuals for Type O blood appeared to be significantly lower, just 26 percent of the cases versus 34 percent of the healthy control group. Side effects of the coronavirus (COVID-19) vaccination Very common side effects in the first day or two include: having a painful, heavy feeling and tenderness in the arm where you had your injection feeling tired headache, aches and chills diarrhoea, nausea and vomiting mild flu-like symptoms The NEJM study analyzed genetic data from more than 1,600 patients who had been hospitalized with severe cases of COVID-19 in Italy and Spain and compared them with about 2,200 uninfected individuals. Post-vaccine symptoms are typically mild and resolve quickly without the need to use any medication. "The resulting brownie is the same, though.". However, as the situation surrounding COVID-19 continues to evolve, it's possible that some data have changed since publication. Some previously young, healthy people who have developed COVID-19 have suffered strokes, possibly due . As seen in patients 3 and 6, a proximal complement inhibitor, such as danicopan, may prevent breakthrough hemolysis precipitated by the vaccine; however, it is equally possible that the stronger immune response after the second vaccine dose was primarily responsible for the breakthrough hemolysis in patient 3. More rarely, you may experience joint pain, swelling or rash at the injection site. Is the COVID-19 thrombotic catastrophe complement-connected? The sore arm can be either due to the trauma of the needle in the muscle, or local inflammation in the muscle probably because of the chemicals in the injection, said Prof Robert Read, head of clinical and experimental sciences within medicine at the University of Southampton and director of the National Institute of Health Researchs Southampton Biomedical Research Centre. Read said: We are a little baffled about this, but it may be due to the fact that the Oxford University/AstraZeneca vaccine has an adenovirus vector, which stimulates the immune system strongly in the first dose and less strongly in the second.. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. - Drug Monographs That is not to say that there have never been safety issues with vaccines. Blood type is not the only factor in disease severity. fatigue for 50% of the participants. While it's not a hard-and-fast rule, CDC officers have made recommendations to Americans to consider delaying receiving this bivalent booster vaccine at least three months from the date of your last COVID-19 infection. COVID Increases Risk of Long-Term Brain Injury, Study Shows. "Some rare side effects such as myocarditis and pericarditis have been shown to be even less common with subsequent booster doses compared to the primary series second dose shot," she adds. According to Australian data collected on the influenza vaccine in 2020, only 5.5% of people reported any adverse event, with just 0.3% being serious enough to see a doctor about. Free download: Get the Body Ecology blood type ebook. And if you didn't experience any side effects at all during your initial vaccine series or from the boosters after, there's a good chance you won't this time around, either. "We all recognize that we're not the same, but we have not been able, on a genetic basis, very often, to determine whether certain people with certain genes are more or less susceptible to get an infection if they're exposed to a germ," said William Schaffner, MD, an infectious disease specialist, and professor at the Vanderbilt University School of Medicine. His last dose of ravulizumab was 4 weeks prior to vaccination. For original data, please e-mail the corresponding author. A bigail, a 29-year-old from New York City who asked to use a pseudonym to preserve her privacy, knew to expect some side effects after she got her second Pfizer-BioNTech COVID-19 vaccine in . Side effects in adults >55 after Pfizer-BioNTech vaccine (second dose) Pain at injection site (66.1%) Fatigue (50.5%) Headache (39.0%) Muscle pain (28.7%) Chills (22.7%) Joint pain (18.9%) Fever (10.9%), diarrhea (8.3%) and vomiting (0.7%) were also reported. Dr. Gundry and her team continue to investigate how heart injuries caused by COVID-19 developand the impact of red blood cells on the infection. I have read that people with certainbloodtypes are more susceptible to contracting COVID-19. "I encourage people who have had COVID once, or even multiple times to still seek out vaccination, as it's going to really optimize the level of protection that you have against getting COVID yet again this fall and winter," he advises. Patient 2 is a 45-year-old man with a 20-year history of PNH. Patients 2, 3, and 4 experienced severe hemolysis with 2 to 4 g/dL hemoglobin decrease. These include: chills fatigue fever. These studies only suggest an association between blood types and Covid-19 outcome, not cause and effect. 4. We call this the viral load. But recently, the genetics company 23andMe revealed preliminary data from their own study showing that a persons blood type, which is determined by the ABO gene, appears to affect susceptibility to coronavirus. What Research Says About the Link Between COVID-19 and Blood Type, What the Blood Link Research Means for You. This suggests that postvaccination hemolysis is not mediated by the direct effect of the spike protein. Additionally on danicopan; however, 2 doses were missed immediately following vaccination. An infection with a lower viral load makes a positive difference in clinical infection in all people. But again, experts say it's too early to know for sure. To test the effect of the SARS-CoV-2 spike protein on hemolysis, we performed erythrocyte lysis using erythrocytes from a patient with PNH and acidified normal human serum (aNHS) with addition of the SARS-CoV-2 spike protein subunit 1 (S1) (see supplemental methods, available on the Blood Web site). This week's topics include a nanoparticle vaccine for COVID, use of dexamethasone and surgical site infections, blood groups and disease . Quite a bit of research has been published on the topic of blood type and its role in determining COVID-19 risk. While this doesnt mean a free pass for anyone with a less susceptible blood type, it might help begin to solve some mysteries over why the coronavirus has more devastating effects on some individuals but not others. The clots may also form in multiple places in the body, including in the lungs. However, the chance of developing severe illness and death after a COVID-19 infection is much higher (2-10%). Does your blood type affect COVID vaccine side effects? Why Trust Us? The secondary outcome was severe COVID-19 illness or death. Please login or register first to view this content. Black colleagues share their reasons for getting the COVID-19 vaccines, 7 steps to prepare for your COVID-19 vaccines, COVID-19 and Its Cardiovascular Impact Rapid Response Grant. Each jar of cultured veggies you make is brimming with immune-boosting potential. Our clinicians do not order blood typing routinely, other than for pregnant patients. They noted that this area also includes a genetic variant associated with increased levels of interleukin-6, which plays a role in inflammation and may have implications for COVID-19 as well. and elicited consistent side effects as compared to other COVID-19 vaccines, according to Dr. Martinello. For A and AB groups, the stay was 13.5 days. Some data suggests this may be the case. Enjoying our content? Register for free and gain unlimited access to: - Clinical News, with personalized daily picks for you Wondering what to do with other vaccines? "The side effects that we see occur early on and that's it," Goepfert said. Whether you know your blood type or not, its still necessary for your sake and the sake of those around you to follow public health precautions, such as handwashing, mask-wearing, physical distancing, and staying home to stay safe. Deep, healing sleep, reducing stress, walking or other forms of gentle exercise, plus pampering yourself, are important for helping to create a robust immune system. These usually last from a few hours to a few days after vaccination. Common Moderna COVID-19 Vaccine side effects may include: fever, chills; redness or a hardness and swelling where the shot was given; swelling or tenderness under your arm; nausea, vomiting; feeling tired; or. In the days following COVID-19 vaccination, your immune system responds to the vaccine. That's because of a particular type of antibody they make that attacks other red blood cells. The clots linked to the vaccine were a dangerous type in the brain, while birth control pills increase the chances of a blood clot in the leg or lung a point quickly noted by many experts. 2. Of course, its not just as simple as saying that anyone with an O blood type has a lower risk of dying of COVID-19. Similarly, type B individuals only have anti-A antibodies. The answer remains elusive but may be connected to how the virus attaches itself to your cells and how your genes influence the number and type of receptors on those cells, as well as to your overall risk of cardiovascular problems. "There's a fairly decent amount of existing literature beyond SARS-CoV-2" that certain blood types can play a role in disease risk and severity, says Joel Ray, M.D., a clinician scientist and professor at St. Michael's . As with all vaccines, side effects may occur after getting the COVID-19 vaccine. By signing up, you are consenting to receive electronic messages from Nebraska Medicine. Joint pain. Of course, your blood type is not a risk factor over which you have any control. The most common were fatigue, headache, and new or worsened muscle pain. Side. "Most side effects are mild or moderate and . This seems to be an issue with DNA adenovirus vector vaccines the biology of which is yet to be fully understood, said Prof Saad Shakir, director of the independent Drug Safety Research Unit. 1 vaccines. Common COVID-19 vaccine side effects include: Redness or soreness at injection site. What this means is that the white blood cells that are stimulated by the vaccine to make antibodies themselves have to secrete chemicals called cytokines, interferons and chemokines, which function to send messages from cell to cell to become activated.. And as for your blood type: If you know you have type A or AB blood, this latest research isnt cause for terror, just as having type O blood doesnt mean you can skip the hand sanitizer and other safety measures. A side effect or reaction isn't necessarily all bad, by the way; it may indicate that the body is building protection against the virus. The other common side-effects the muscle aches, flu-like illness and fatigue are probably due to generalised activation of the immune system caused by the vaccine. If not, you can order an inexpensive kit to test your blood at home by pricking your finger to get a small blood sample, which you can then mix with antibodies to the A and B antigens that come on the card.