This causes the same reaction as the histamine release due to allergy. The iodine or barium in contrast dye is very dense and "absorbs" X-ray photons at a greater rate than the body's soft tissues. Iodinated contrast media are toxic to the kidneys and kidney functions. Obviously speak with your physician about what to do. The body part with the contrast inside will appear lighter on the radiographic image than the surrounding tissue. Sometimes, contrast dye (or contrast) is used in imaging scans to help your doctors see your organs better. "Iodine allergy" is often used as a collective term for adverse reactions to these agents. Computed tomography (CT) scans and magnetic resonance imaging (MRI) use different kinds of contrast. Requesting / Referring Physician to prescribe Premedication, to be initiated prior to the CT exam. Author: Prof Stacy Goergen* What is contrast medium? Contrast media (sometimes called contrast agents or dye) are chemical substances used in medical X-ray, magnetic resonance imaging (MRI), computed tomography (CT), angiography, and occasionally ultrasound imaging. Some of it depends on how bad the kidney disease IS and what type. The high concentration of the contrast can shock cells called basophils into releasing their granules filled with histamine. About Contrast Dye. The higher the iodine concentration, the greater the risk of an adverse reaction. The increasing concerns for using gadolinium-based contrast agents in patients with renal or liver disease is urging researchers to find an alternative. I believe there are some options out there. Has anyone had a similar problem and if so how did you overcome it. 9. Rather, contrast media act to directly release histamine and other chemicals from mast cells. A non-iodinated contrast media is one that does not contain iodine and may instead contain barium or other non-iodinated media as the radio opaque substance. locations for imaging of patients with prior history of allergy to iodine. Hi all, I urgently need to have a scan of abdomen and pelvic area, but I’m allergic to the iodine contrast dye that they inject. Foss • • 16 Replies. Having a reaction to an iodine-based contrast dye is also not the same as an allergy to seafood, which may be rich in iodine. ... is there another alternative to this dye. Not a doctor; responding to A2A. 3. The iodine concentration has an effect on the severity of an adverse reaction. Shellfish allergy has nothing to do with iodine or contrast. Alternative to iodine contrast for CT colonograghy ? 4. Low osmolality contrast & premedication helps. 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